Dissecting genetic basis of common multifactorial disorders is the main challenge in the field of medical genetics. Genetic association studies are the main tool for finding variants affecting the liability of common diseases and predisposition of devastating non-communicable disorders. On the other hand, advances in molecular medicine and unraveling new molecular pathways in pathogenesis of such diseases necessitate focusing on personalized medicine as a voluble approach at the clinical level. This in turn can be affected by different characteristics of the population. Appropriate design of genetic studies is the key for a successful outcome. Several population-based studies have been done in our department and the ongoing research involves association studies on well-characterized samples of common diseases including CAD and cancers. Molecular Medicine group at the Department of Modern Sciences and technologies can offer a short term course (100 hours on a flexible basis) on principles of designing and setting up genetic association studies.
For more information, please refer to the department website or contact the course organizer
The core programme includes taught courses and workshops about the following subjects:
1. Genetic basis of disease
2. Molecular Medical Genetics
3. Molecular Epidemiology
4. Association studies:
a. Design and setting up
b. Finding appropriate candidate genes
c. Bioinformatics and using databases
d. Sampling and sample size calculation
e. Risk calculation
f. Statistical analysis and related software